Xinjie Hui

09/2014 - 07/2019      Shenzhen University, Bachelor's degree in Medicine
09/2019- 07/2022      Xuanwu Hospital, Capital Medical University, Master's degree in Medicine
09/2022 - present      Peking Union Medical College Hospital, PhD candidate


Research interest

(1) Statistics and its application in omics and precision medicine;
(2) Feature selection and applications;
(3) Clinical and mechanistic research of Obstructive Sleep Apnea (OSA).


Publications and Patents

Hui X, Cao W, Xu Z, Guo J, Luo J, Xiao Y. Hypoxic indices for obstructive sleep apnoea severity and cardiovascular disease risk prediction: A comparison and application in a community population. Respirology. 2024 May 21. Pubmed

Dai L, Guo J, Hui X, Wang X, Luo J, Huang R, Xiao Y. The potential interaction between chemosensitivity and the development of cardiovascular disease in obstructive sleep apnea. Sleep Med. 2024 Feb. Pubmed

Zhu RX, Nie XH, Liu XF, Zhang YX, Chen J, Liu XJ, Hui XJ. Short-term effect of particulate matter on lung function and impulse oscillometry system (IOS) parameters of chronic obstructive pulmonary disease (COPD) in Beijing, China. BMC Public Health. 2023 Jul 24. Pubmed

Guo Y, Kang M, Hui X, Fan X, Zhang L, Wang Y, Wang R, Nie X. The Association Between Cognition of Obstructive Sleep Apnea Patients and Urinary AD7c-NTP Level: Investigation and Application. J Alzheimers Dis. 2022 Sep. Pubmed

Qiu L, Liang C, Zheng Y, Kang H, Chen A, Chen C, Wang X, Yang J, Fang Q, Hui X, Hu Y, Chen Z, Sha O, Zhu WG, Wang Y. Identification of Human Global, Tissue and Within-Tissue Cell-Specific Stably Expressed Genes at Single-Cell Resolution. Int J Mol Sci. 2022 Sep. Pubmed

Chen Z, Zhao Z, Hui X, Zhang J, Hu Y, Chen R, Cai X, Hu Y, Wang Y. T1SEstacker: A Tri-Layer Stacking Model Effectively Predicts Bacterial Type 1 Secreted Proteins Based on C-Terminal Non-repeats-in-Toxin-Motif Sequence Features. Front Microbiol. 2022 Feb 8. Pubmed

Hui X, Chen Z, Zhang J, Lu M, Cai X, Deng Y, Hu Y, Wang Y. Computational prediction of secreted proteins in gram-negative bacteria. Comput Struct Biotechnol J. 2021 Mar 22. Pubmed

Liu X, Hui X, Kang H, Fang Q, Chen A, Hu Y, Lu D, Chen X, Wang Y. A MultiGene Model Effectively Predicts the Overall Prognosis of Stomach Adenocarcinomas With Large Genetic Heterogeneity Using Somatic Mutation Features. Front Genet. 2020 Aug 26. Pubmed

Hui X, Chen Z, Lin M, Zhang J, Hu Y, Zeng Y, Cheng X, Ou-Yang L, Sun MA, White AP, Wang Y. T3SEpp: an Integrated Prediction Pipeline for Bacterial Type III Secreted Effectors. mSystems. 2020 Aug 4. Pubmed

Hu Y, Shu XS, Yu J, Sun MA, Chen Z, Liu X, Fang Q, Zhang W, Hui X, Ying Y, Fu L, Lu D, Kumar R, Wang Y. Improving the diversity of captured full-length isoforms using a normalized single-molecule RNA-sequencing method. Commun Biol. 2020 Jul 30. Pubmed

Zhong Q, Fang J, Huang Z, Yang Y, Lian M, Liu H, Zhang Y, Ye J, Hui X, Wang Y, Ying Y, Zhang Q, Cheng Y. A response prediction model for taxane, cisplatin, and 5-fluorouracil chemotherapy in hypopharyngeal carcinoma. Sci Rep. 2018 Aug 23. Pubmed

Zhou L, Hui X, Yuan H, Liu Y, Wang Y. Combination of Genetic Markers and Age Effectively Facilitates the Identification of People with High Risk of Preeclampsia in the Han Chinese Population. BioMed Res Int. 2018 Jun 11. Link

Zhang S, Xu Y, Hui X, Yang F, Hu Y, Shao J, Liang H, Wang Y. Improvement in prediction of prostate cancer prognosis with somatic mutational signatures. Journal of Cancer. 2017 Aug 29. Pubmed

Guo Z, Cheng X, Hui X, Shu X, White AP, Hu Y, Wang Y. Prediction of new bacterial type III secreted effectors with a recursive Hidden Markov Model profile-alignment strategy. Current Bioinformatics. 2017 Jul 24. Link

Hui X, Hu Y, Sun MA, Shu X, Han R, Ge Q, Wang Y. EBT: A Statistic Test Identifying Moderate Size of Significant Features with Balanced Power and Precision for Genome-wide Rate Comparisons. Bioinformatics. 2017 May 3. doi: 10.1093/bioinformatics/btx294. Pubmed

Hu Y, Huang H, Hui X, Cheng X, White AP, Zhao Z, Wang Y. Distribution and Evolution of Yersinia Leucine-Rich Repeat Proteins. Infect Immun. 2016 Jul 21;84(8):2243-54. Pubmed


Wang Y, Hui X. Registration of Software Copyrights for EBT (No. 2017SR206343).

Wang Y, Hui X. Registration of Software Copyrights for LUdiff (No. 2018SR054556).

Xiao Y, Hui X. Registration of Software Copyrights for SBII (No. 2024SR0360961).


Awards and Honors

(1) Supported by a Guangdong Provincial Climb Plan Funding Key Project (2018)
(2) Special Prize, Shenzhen University Undergraduate Challenge Cup 2017
(3) Selected to be presented in the 10th Annual Meeting of the Chinese College Students' Innovation and Entrepreneurship (2017)
(4) College Students National Scholarship 2017
(5) Supported by a Guangdong Provincial Climb Plan Funding (2017; major participant)
(6) Second Prize, Shenzhen University Undergraduate Challenge Cup 2016
(7) Supported by a Chinese National Undergraduate Training Programs for Innovation and Entrepreneurship (201510590049)
(8) Excellence for the appraisal at the end of research project 201510590049





2016-2018 All Rights Reserved
HCD Laboratory
Shenzhen University Health Science Center
Email: wangyj@szu.edu.cn